Contact via Land Line at     (501) 745-6341               Social

Cell Voice or Text  at            (501) 253-5058           Media

Twitter
Facebook
Clearing the Smoke and Mirrors  of  80 YEARS of FALSE INFORMATION !

Talk Cannabis And Politics Marijuana Education: Federal Information

US Patent #7999107

Publication number US7999107 B2     Publication type Grant
Application number US 12/009,114     Publication date 16 Aug 2011
Priority date 31 Jan 2007     Fee status Lapsed
Also published as CA2676167A1, CA2676167A1, DE602008005405D1, EP2109615A1, EP2109615B1, US20080207666, WO2008094476A1
Inventors John S. Debenham, 5 More »
Original Assignee Merck Sharp & Dohme Corp.
Export Citation BiBTeX, EndNote, RefMan
Patent Citations (26), Non-Patent Citations (19), Referenced by (1), Classifications (10), Legal Events (5)
External Links: USPTO, USPTO Assignment, Espacenet (European P.O.)


Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators
US 7999107 B2


Abstract
Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, Alzheimer's disease, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, Huntington's disease movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, cirrhosis of the liver, non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and the promotion of wakefulness.

BACKGROUND OF THE INVENTION

Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. .............

http://www.hitwebcounter.com/
Counter For Wordpress